(1-(4-chloro-2-fluorophenyl)cyclobutyl)methanamine hydrochloride
(1-(4-chloro-2-fluorophenyl)cyclobutyl)methanamine hydrochloride
CAS: 1500157-65-2
Molecular Formula: C11H13ClFN
(1-(4-chloro-2-fluorophenyl)cyclobutyl)methanamine hydrochloride - Names and Identifiers
| Name | (1-(4-chloro-2-fluorophenyl)cyclobutyl)methanamine hydrochloride |
| Synonyms | (1-(4-chloro-2-fluorophenyl)cyclobutyl)methanamine hydrochloride |
| CAS | 1500157-65-2 |
(1-(4-chloro-2-fluorophenyl)cyclobutyl)methanamine hydrochloride - Physico-chemical Properties
| Molecular Formula | C11H13ClFN |
| Molar Mass | 213.68 |
(1-(4-chloro-2-fluorophenyl)cyclobutyl)methanamine hydrochloride - Introduction
(1-(4-chloro-2-fluorophenyl) cyclomutyl) methanamine hydrochloride is an organic compound that contains a methylamine group and a cyclobutyl group in its chemical structure. The following is a description of its nature, use, preparation and safety information:
Nature:
(1-(4-chloro-2-fluorophenyl)cyclobutyl)methanamine hydrochloride is a white or off-white solid powder. It can form a colorless or slightly yellow solution when dissolved in water or some organic solvents. Its molecular formula is C12H14ClFN • HCl.
Use:
(1-(4-chloroo-2-fluorophenyl) cyclomutyl) methanamine hydrochloride is commonly used in the field of medicine as an intermediate or raw material of antipsychotic drugs. It can be involved in the synthesis of many drugs, such as anti-anxiety drugs and drugs to treat depression, etc.
Method:
The preparation of (1-(4-chloro-2-fluorophenyl) cyclomutyl) methanamine hydrochloride can be carried out by synthetic routes. A common preparation method is to react fluorobenzene and cyclobutanol to form cyclobutyl benzyl alcohol, and then react the intermediate with 4-chlorobenzaldehyde, (1-(4-Chloro-2-fluorophenyl) cyclobutyl) Methanol is produced. Subsequently, this methanol is subjected to a condensation reaction with methylamine to produce (1-(4-chloro-2-fluorophenyl) cyclobutyl) methylamine. Finally, by reaction with hydrochloric acid, its hydrochloride is prepared.
Safety Information:
(1-(4-chloro-2-fluorophenyl) cyclomutyl) methanamine hydrochloride requires attention to safe operation during use. It may be toxic to the human body, so it is recommended to wear appropriate protective measures, such as protective gloves and glasses, during contact or operation. At the same time, avoid direct contact with skin and eyes, and maintain good ventilation. In case of accidental exposure or inhalation, take appropriate first aid measures immediately and seek medical attention. When storing, it should be kept in a dry, cool, ventilated place, away from fire and flammable materials.
Nature:
(1-(4-chloro-2-fluorophenyl)cyclobutyl)methanamine hydrochloride is a white or off-white solid powder. It can form a colorless or slightly yellow solution when dissolved in water or some organic solvents. Its molecular formula is C12H14ClFN • HCl.
Use:
(1-(4-chloroo-2-fluorophenyl) cyclomutyl) methanamine hydrochloride is commonly used in the field of medicine as an intermediate or raw material of antipsychotic drugs. It can be involved in the synthesis of many drugs, such as anti-anxiety drugs and drugs to treat depression, etc.
Method:
The preparation of (1-(4-chloro-2-fluorophenyl) cyclomutyl) methanamine hydrochloride can be carried out by synthetic routes. A common preparation method is to react fluorobenzene and cyclobutanol to form cyclobutyl benzyl alcohol, and then react the intermediate with 4-chlorobenzaldehyde, (1-(4-Chloro-2-fluorophenyl) cyclobutyl) Methanol is produced. Subsequently, this methanol is subjected to a condensation reaction with methylamine to produce (1-(4-chloro-2-fluorophenyl) cyclobutyl) methylamine. Finally, by reaction with hydrochloric acid, its hydrochloride is prepared.
Safety Information:
(1-(4-chloro-2-fluorophenyl) cyclomutyl) methanamine hydrochloride requires attention to safe operation during use. It may be toxic to the human body, so it is recommended to wear appropriate protective measures, such as protective gloves and glasses, during contact or operation. At the same time, avoid direct contact with skin and eyes, and maintain good ventilation. In case of accidental exposure or inhalation, take appropriate first aid measures immediately and seek medical attention. When storing, it should be kept in a dry, cool, ventilated place, away from fire and flammable materials.
Last Update：2024-04-09 21:11:58
